The Prenatal Biochemistry Laboratory at BC Children's and BC Women's performs the serum biochemistry testing and the reporting of SIPS, IPS and Quad screen results.
Current Version - The lab requisition was updated (in June 2017) to reflect that the Part 2 (or Quad) serum collection can now be done earlier, starting at week 14. Part 2 blood can be now collected from 14+0 - 20+6 weeks. For optimal but still early results, women should aim to have their Part 2 blood collected from 15+0 -16+0 weeks. A risk calculation for Down syndrome and open neural tube defect can then be reported as early as 16-17 weeks, which provides additional decision-making time if more testing is warranted (such as NIPT or Amnio).
Print out a lab requisition and fill it out manually, or download an interactive lab requisition to fill out on the computer and then print out.
Give the completed requisition(s) to your patient to accompany their blood sample to the laboratory. Each blood sample must be accompanied by a completed requisition.
View a sample prenatal screen report.
The report shows screen negative and screen positive results for Down syndrome and open neural tube defects. The report does not display results for trisomy 18 unless the result is screen positive. Note - if Part 2 serum is collected in week 14, MS-AFP is used to assess for ONTD as usual but an ONTD risk calculation will not be shown on the report; instead, comments will appear to indicate whether its negative or positive.
Screen positive results are called out to the ordering health care provider by genetic counsellors in the Prenatal Biochemistry Laboratory as soon as results are known.
Reports are faxed to the ordering health care provider and to the “copy to” providers listed on the requisition. Hard copies will not be mailed.